Pulmonary Fibrosis
Pulmonary Fibrosis is a group of progressive lung disorders characterised by irreversible scarring that can ultimately lead to respiratory failure. In Idiopathic Pulmonary Fibrosis (IPF), median survival after diagnosis is only three to five years. Disease progression varies considerably between patients, and although antifibrotic therapies can slow progression, there is currently no cure.
By integrating clinical, imaging and molecular data, AIRIS will support predictive models and clinically relevant hypotheses to better understand disease progression and treatment response. This could contribute to patient-specific digital twins and more individualised predictions of disease progression and therapeutic response. Generated hypotheses will be assessed for plausibility and novelty and complemented by biological cross-validation, supporting a proof of concept for AI-enabled precision medicine in pulmonary fibrosis.
Expert teams evaluating AIRIS usability in Pulmonary Fibrosis:Yale, KU Leuven, ICS-HUB, CHUV, UNIBO, AUSL Romagna




